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The Role of Vial Dimension in Minimizing Dead Volume Effects in Autosamplers

The Role of Vial Dimension in Minimizing Dead Volume Effects in Autosamplers

CARRYOVER MITIGATION USING NEEDLE WASH SOLVENT CHEMISTRY AND

onto the outside of the needle. A key attribute of modern autosamplers is the ability to effectivity remove sample from all active surfaces of the autosampler. The design of the sample flow path in the autosampler, features controlling needle washing, and the chemistry of the wash solvent all play a role in eliminating detectable carryover.

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The Role of Vial Dimension in Minimizing Dead Volume Effects in Autosamplers

The Role of Vial Dimension in Minimizing Dead Volume Effects

These one-piece microvials have a very low residual volume due to a specially shaped deep and narrow inner reservoir which collects the liquid in the base so compatible autosamplers can collect all but 1-2 microliters of sample while having a total sample volume of 1.2mL.

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The Role of Vial Dimension in Minimizing Dead Volume Effects in Autosamplers

Should FDA Reconsider Allowing the Pooling of COVID-19

Mar 24, 2021 · In 2006, Strauss et al. described “the critical role of the syringe” during a pandemic, such as an influenza pandemic, and found that an LDV syringe could provide up to 19% additional vaccine (influenza) doses per vial when 10-dose vials were used. 8 This could equate to thousands or even millions of additional people becoming vaccinated

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The Role of Vial Dimension in Minimizing Dead Volume Effects in Autosamplers

LC Method Translation - the Dwell Volume - Aijiren Community

For both methods, the dwell time is multiplied by the flow to get the dwell volume. Dwell volume vs. dead volume. Don't confuse dead volume with dwell volume. The dead volume is only part of it—the volume from the injector to the column head. References "Measure the dwell volume", European Pharmacopoeia 7.0, 2.2.46.

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The Role of Vial Dimension in Minimizing Dead Volume Effects in Autosamplers

FAQ for Optimizing COVID-19 Vaccine Preparation and Safety - ASHP

mL or less of dead volume. Practice settings have reported success using a combination of at least 3 LDV syringes (creating dead volume of 0.105 mL or less) and 3 non-LDV syringes for vaccine withdrawal. The Frequently Asked Questions below are intended to address common questions related to dead volume and optimizing number of doses per vial

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The Role of Vial Dimension in Minimizing Dead Volume Effects in Autosamplers

LOW DEAD-VOLUME SYRINGES AND/OR NEEDLES

In order to ensure consistent withdrawal of 6 doses of 0.3 mL, it is important to adhere to minimizing volume loss during dose extraction. If standard syringes and needles are used, there may not be sufficient volume to extract a 6th dose from a single vial.1† Dead volume (also called ‘dead space’) is the amount of fluid remaining within the

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The Role of Vial Dimension in Minimizing Dead Volume Effects in Autosamplers

autosampler vial - Hplc Vials

Aijiren sample vials design is characterized by universal ease of use, especially the use of automated sample introduction systems, so this type of vial is also called an autosampler vial. And this sample vial is extremely compatible. The 1.5ml sample vial we usually say is the 2ml volume sample vial.

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The Role of Vial Dimension in Minimizing Dead Volume Effects in Autosamplers

GC Autosampler | Labcompare.com

There are GC autosamplers that can do all three types of autosampling. The types of samples you will be analyzing will dictate which type of autosampler you will need. Keep in mind the sample size you wish to use, how many analyses need to be run in a given time, and if there are different types of samples that would require a multipurpose

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The Role of Vial Dimension in Minimizing Dead Volume Effects in Autosamplers

minimum volume of sample should hplc sampler vials

Autosamplers, Part II — Problems and SolutionsAug 22, 2014 for liquid chromatography (LC). This if a sample vial is filled too full and sealed ... removed volume must be repl

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The Role of Vial Dimension in Minimizing Dead Volume Effects in Autosamplers

Autosamplers, Part II — Problems and Solutions

a vial septum and then installing the vial in the sample tray. I adjust the needle to the target depth, then lift the vial by its cap. In the case of my instrument, I expect approximately 1 mm of vertical play if the system is adjusted properly. This play allows a safety margin in case of any variation in vial depth for a given vial model. This

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The Role of Vial Dimension in Minimizing Dead Volume Effects in Autosamplers

LC Troubleshooting Series Autosamplers and Injections - Aijiren

- Check your sample volume to ensure you have enough in the vial to reach the needle - Check valves and metering syringes for leaks . To validate autosampler accuracy, install a tared vial and inject a volume that is conveniently verified gravimetrically. For manual injections, if pea ks are too small, check the needle port for leaks.

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The Role of Vial Dimension in Minimizing Dead Volume Effects in Autosamplers

Vials Catalogue v10 - MilliporeSigma

Autosampler vials are classified by the diameter of the body of the vial, the height of the vial, and, the thread finish. Vial volumes are nominal. For example, various manufacturers describe a 12mm x 32mm vial as having a volume of 1.5 mL, 1.8 mL, or 2 mL. Clear glass and amber glass offer essentially the same inertness.

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The Role of Vial Dimension in Minimizing Dead Volume Effects in Autosamplers

InMotion™ Autosamplers - Overview - METTLER TOLEDO

Combined with the InMotion™ Autosampler Flex Base and 100 mL Rack; the Chemical Oxygen Demand Kit is designed to work with your digestion vials for a Datasheet: InMotion Karl Fischer Kit Combined with any of the InMotion 100 mL racks, the Karl Fischer Kit allows for direct titration of solid and liquid samples in the titration beaker....

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The Role of Vial Dimension in Minimizing Dead Volume Effects in Autosamplers

Sigma hplc vial caps in clear for HPLC and GC supplier

Hplc Systems Vial - manufacturer, factory, supplier from China. 60ML Free Samples Glass Vials. 2ml Analysis Clear Technology and Science Vial. 13-425 4ml Glass vials for HPLC Analysis. 20ml Headspace Autosampler Vials Screw Thread for GC. Pharma Analisis 4ML Screw Thread Vial. Free Samples ND9 Screw Vials with Caps.

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The Role of Vial Dimension in Minimizing Dead Volume Effects in Autosamplers

GUIDELINES FOR AUTOSAMPLER VIAL SELECTION

vial full. The dimensions for 12x32mm vials are standard between manufacturers but the length of the neck and width/shape of the vial shoulder may vary. 12x32mm microvials have the same outer dimensions but the inside of the vial may be tapered to reduce volume or contain a fused insert.

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